ea0016p25 | Adrenal | ECE2008
Ziegler Christian G
, Langbein Heike
, Vukicevic Vladimir
, Bornstein Stefan R
, Ehrhart-Bornstein Monika
, Krug Alexander W
Within the adrenal gland, chromaffin cells and their progenitors are exposed to a wide variety of growth factors and hormones, including adrenal androgens such as DHEA. The DHEA producing-zona reticularis of the adrenal cortex is in close proximity to the neural crest-derived catecholamine-producing chromaffin cells of the medulla, enabling strong paracrine interactions. In vivo studies in humans revealed that congenital adrenal hyperplasia due to 21-hydroxylase ...